#Patientcomfort 05. Oct 2021

25 years of Straumann® Emdogain: How matrix proteins led to the breakthrough in regenerative periodontal therapy

This year marks a special anniversary in the world of dentistry with the 25-year anniversary of Emdogain®, a unique gel with enamel matrix proteins. Since its launch, more than two and a half million people have benefited from this outstanding product [1] used in regenerative procedures in periodontology and implantology. And its success continues unabated: every three minutes someone, somewhere in the world is undergoing Emdogain® treatment.

Sound scientific evidence

More than 600 human studies and over 1,000 peer-reviewed publications, including 10-year data and human histological examinations2,3, have confirmed the efficacy of the natural protein matrix. Emdogain® supports the cellular biological processes associated with the development of the periodontium and stimulates certain cell types involved in the wound healing cascade of soft and hard tissue regeneration. It enables efficient regeneration both with and without flap formation resulting in the preservation of teeth over the long term and sustainably improved esthetic results.

All you have ever wanted to know about Emdogain® – join us on a discovery trip to Emdogain’s origins in Sweden and the impressive milestones of its career as the widely accepted gold standard in periodontal regeneration.

Destination 1: Recognition

What do international experts in periodontology think about Emdogain®?

Destination 2: Origins

Who invented Emdogain®? We will give you a clue: It all started in the 90s in a Swedish biotech lab…

Destination 3: Mode of Action

Understanding the principle of “molecular mimicry”.


“Emdogain® is a gold standard with the most sound evidence of all biological materials. I recommend it to any clinician working in periodontal regeneration.”

Prof. Dr. Anton Sculean, University of Bern/Switzerland



Destination 4: Legacy

The new Emdogain® FL for flapless procedures is predicated on the success of its surgical application.

Destination 5: Indications

What are the indications of Emdogain® and Emdogain® FL? When to use the surgical approach and when to go flapless.

Emdogain® on Youtube

Watch our playlist of Emdogain®-related video clips and learn more about the amazing technology behind.

And last but not least… The Emdogain® Song is probably the only musical piece ever dedicated to a regenerative dental material (please correct us, if we are wrong)! “The Emdogain Song” was written and performed by Dr. Antonios Zampelis, covering Creedence Clearwater Revival’s track “Have you ever seen the rain”.

References:

  1. Straumann Product Information
  2. Sculean A, Kiss A, Miliauskaite A, Schwarz F, Arweiler NB, Hannig M. Ten-year results following treatment of intra-bony defects with enamel matrix proteins and guided tissue regeneration. J Clin Periodontol. 2008 Sep;35(9):817-24. doi: 10.1111/j.1600-051X.2008.01295.x.
  3. McGuire MK, Scheyer ET, Nunn M. Evaluation of human recession defects treated with coronally advanced flaps and either enamel matrix derivative or connective tissue: comparison of clinical parameters at 10 years. J Periodontol. 2012 Nov;83(11):1353-62. doi: 10.1902/jop.2012.110373