STUDY OBJECTIVES AND METHODS
The purpose of this study was to analyze the effect of implant surface characteristics on osseointegration and crestal bone formation in a grafted dehiscence defect minipig model. A standardized 3 mm × 3 mm acute-type buccal dehiscence minipig model grafted with deproteinized bovine bone mineral and covered with a porcine collagen membrane after 2 and 8 weeks of healing was utilized. Crestal bone formation was analyzed histologically and histomorphometrically to compare three implant groups: (1) a novel, commercially available, gradient anodized (NGA) implant, to two custom-made geometric replicas of implant "1," (2) a superhydrophilic micro-rough large-grit sandblasted and acid-etched surface, and (3) a relatively hydrophobic microrough large-grit sandblasted and acid-etched surface.
RESULTS
- At 2 and 8 weeks, there was no difference between the amount and height of newly formed bone (NBH, new bone height; BATA, bone area to total area) for any of the groups (p > 0.05).
- First bone-to-implant contact (fBIC) and vertical bone creep (VBC) at 2 and 8 weeks were significantly increased for
- Groups 2 and 3 compared to Group 1 (p < 0.05).
- At 8 weeks, osseointegration in the dehiscence (dehiscence bone-implant-contact; dBIC) was significantly higher for
- Groups 2 and 3 compared to Group 1 (p < 0.05).
CONCLUSIONS
The amount of newly formed bone (BATA) and NBH was not influenced by surface type. However, moderately rough surfaces demonstrated significantly superior levels of osseointegration (dBIC) and coronal bone apposition (fBIC) in the dehiscence defect compared to the NGA surface at 2 and 8 weeks.
Adapted from S Shahdad et al., Clin Oral Implants Res. 2024 Oct 10, for more info about this publication click HERE
This review is part of the Straumann "Scientific Highlights Newsletter 6/24"