#Education 03. Oct 2025

Analysis of bone dimensional stability after two-stage maxillary sinus floor augmentation with autogenous bone versus bovine bone mineral combined with autogenous bone chips

By Isabella Neme Ribeiro Dos Reis, Anouck Jue, Eppo Wolvius, Justin Pijpe, Rubens Spin-Neto, Ronald Ernest Jung, Nadja Naenni, Franz J Strauss, Brend Jonker. A selected scientific recommendation by Dr. Marcin Maj.

STUDY OBJECTIVES AND METHODS

The purpose of this study was to compare the dimensional stability of augmented bone following maxillary sinus floor augmentation (MSFA) using autogenous bone (AB) alone or bovine bone mineral combined with locally harvested AB chips (BBM), one year after implant loading. A secondary analysis of a split-mouth, multicenter randomized controlled trial was conducted among 20 patients (40 implants). CBCT/CTs were used to measure bone height (buccal and palatal aspects) and bone area at the implant center at two time points: before implant placement (4-6 months post-MSFA, T1) and 12 months post-implant loading (T2). Residual bone height and sinus width at 1, 5, and 10 mm from the crest were also recorded. Linear regression models with generalized estimating equations were used to assess the influence of graft material (AB and BBM), initial graft dimensions and sinus width on dimensional changes.

RESULTS

  • Adjusted regression models showed that AB-treated sites experienced significantly greater reductions in graft height (mean difference at buccal sites: -1.76 mm [95 % CI, -0.86 to -2.65]; p-value = <0.001); mean difference at palatal sites: -1.82 mm [95 % CI -0.75 to -2.88]; p = 0.001; and bone area (mean difference -17.80 mm² [95 % CI -6.61 to -28.99]; p = 0.002) compared to BBM.
  • Greater initial graft height and area were associated with reduced dimensional changes (p < 0.001) especially when using BBM.
  • Sinus width, measured 10 mm from the crest, was modestly but significantly associated with changes in bone height (p = 0.020), but not with changes in bone area (p = 0.147).
     

CONCLUSIONS

MSFA using BBM combined with autogenous bone chips resulted in greater dimensional stability compared to AB alone.

Adapted from I Neme Ribeiro Dos Reis et al., J Dent. 2025 Sep:160:105889, for more info about this publication, click HERE.

This review is part of the Straumann "Scientific Highlights Newsletter 4/25".

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